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It is foolish to be too certain of the natural order of
things. Once the "Book of Life" is finally completed, we are
expected to end up with between 30 000 and 40 000 genes Faced by a patient with recurrent low back pain, 80% of doctors would
reach for an x ray form and put in a referral for lumbar radiography. Most doctors (88%) do this to reassure patients; nearly
as many (78%) do it to reassure themselves. But radiography of the
spine, as Kendrick and colleagues point out (p 400), is not associated
with improved functioning, severity of pain, or overall health status
of the patient. Radiography does have two effects, however: it
increases patients' satisfaction and increases doctors' workload. The
challenge for doctors is to reassure patients without recourse to radiography.
Psychiatric questionnaires that assess anxiety and depression are
another frequently used investigation. In theory, they are a simple and
inexpensive method of improving recognition, management, and outcome of
psychiatric disorders in non-psychiatric settings. But Gilbody and
colleagues (p 406) find that the reality is different. Clinicians are
often reluctant to act on a positive finding, and if they have not been
trained in psychiatry they lack confidence in dealing with what they
find, resulting in no effect on patient outcome. Depression would be
altogether better treated, argues Andrews (p 419), if clinicians
managed it as a chronic disease rather than a succession of acute episodes.
A concept that might also be fresh to readers is put forward by
Fagot-Campagna and Venkat Narayan (p 377). "Type 2 diabetes mellitus
in children," they tell us, "is an emotionally charged issue and an
emerging public health problem." It is a childhood chronic disease
that primary care workers should watch out for. The prevalence is
rising in North America, and data from Japan suggest that its incidence
in schoolchildren has almost doubled in two decades.
If you visit our website this week you will find a paper that presents
evidence against the link between the MMR vaccine and autism
barely
double that of the nematode worm, which has 18 000 (p 381). Only
0.2% of those genes are responsible for individual variation. We are
not as well endowed with genes as we thought, or had hoped. In its own way, this week's issue challenges convention, in print and on the web.
you will
not find it in this week's print version of the BMJ, but
you will next week. The internet offers rapid publication, free of
those time constraints in the paper world that frustrate both authors
and readers. We consider articles for fast track review and
publication, and posting the most important or timely ones on our
website, ahead of print publication, means the process can be even quicker.
Footnotes
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