Antiplatelet drugs lower the risk of pre-eclampsia

Previous reviews have concluded that antiplatelets are not effective in reducing risks of pre-eclampsia. Duley et al (p 329) report a systematic review including data from over 30 000 women in 39 studies. Antiplatelet drugs were associated with a 15% reduction in the risk of pre-eclampsia, a 14% reduction in the risk of a stillbirth or neonatal death, and an 8% reduction in the risk of preterm birth. Further research is needed to clarify which women benefit most and when treatment should be started.


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Relevant Article

Antiplatelet drugs for prevention of pre-eclampsia and its consequences: systematic review
Lelia Duley, David Henderson-Smart, Marian Knight, and James King
BMJ 2001 322: 329-333. [Abstract] [Full Text] [PDF]




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