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The normal bacterial flora of the mucous membranes is important in
preventing infections. Roos et al (p 210) studied the
recolonisation of otitis prone children with
streptococci after
antibiotic treatment. They showed that a greater number of patients
were healthy and had a normal tympanic membrane compared with those given placebo. Antibiotics that influence the normal flora might paradoxically contribute to recurrent infection. Therefore, restoration of the normal flora would be the logical way to prevent further recurrences of otitis media.
streptococci on recurrences of acute and secretory otitis media in children: randomised placebo controlled trial