Lisinopril is effective in preventing migraine
Some drugs for hypertension (
blockers) or epilepsy are already used
to prevent migraine but may have troublesome side effects. Schrader et
al (p 19) tested the antihypertensive drug lisinopril, an angiotensin
converting enzyme inhibitor, for its efficacy against migraine in 60 patients. Nearly a third of patients had a significant reduction in
frequency of migraine attacks, and side effects, mostly related to
lowering of the blood pressure, were few and mild in most patients. The
drug, already widely used for treating hypertension, may become a
useful adjunct for treating migraine.
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- Prophylactic treatment of migraine with angiotensin converting enzyme inhibitor (lisinopril): randomised, placebo controlled, crossover study
- Harald Schrader, Lars Jacob Stovner, Grethe Helde, Trond Sand, and Gunnar Bovim
BMJ 2001 322: 19.[Abstract] [Full Text] [PDF]
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