Osteoarthritis of the hip is under strong genetic influence

The development of hip osteoarthritis, a major cause of pain and disability, is likely to be multifactorial. Lanyon et al (p 1179) report on a substantially increased risk of hip osteoarthritis among the siblings of patients who had undergone a hip replacement. Their findings support the hypothesis that the development of hip osteoarthritis is under strong genetic influence, although it is also possible that this familial aggregation of disease could be explained by non-genetic factors. The immediate clinical relevance of these results is in the identification of family history as a major risk factor.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to StumbleUpon StumbleUpon   Add to Technorati Technorati    What's this?

Relevant Article

Assessment of a genetic contribution to osteoarthritis of the hip: sibling study
Peter Lanyon, Kenneth Muir, Sally Doherty, and Michael Doherty
BMJ 2000 321: 1179-1183. [Abstract] [Full Text] [PDF]

Access jobs at BMJ Careers
Whats new online at Student BMJ