Lipid lowering for heart attack works best in those at high risk
The proper role of drug treatment for lipid disorders in the primary
prevention of coronary heart disease remains controversial. On p 983
Pignone et al present an updated meta-analysis of four major trials
showing that drug treatment reduces the relative risk of non-fatal and
fatal myocardial infarctions by about 30% but has little or no effect
on all cause mortality over five to seven years. These findings show
that drug treatment has more effect in patients with higher baseline risk.
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- Use of lipid lowering drugs for primary prevention of coronary heart disease: meta-analysis of randomised trials
- Michael Pignone, Christopher Phillips, and Cynthia Mulrow
BMJ 2000 321: 983-986.[Abstract] [Full Text] [PDF]
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