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Several ecological studies have found higher rates of hip
fracture in communities with fluoridated water. Such studies, however, have design flaws, and a prospective study was needed to evaluate the
impact of fluoridation on fracture rates. Given our widespread exposure
to fluoridation, the impact of fluoride on fracture rates is an
important public health issue. Phipps et al (p 860) compared bone
mineral density and incident fracture rates for 2563 women with no
exposure to fluoridation and 3218 women with continuous exposure. Women
with continuous exposure had higher bone mineral density at the lumbar
spine and hip and a slightly reduced risk of hip and vertebral
fractures. This study supports the safety of fluoridation as a public
health measure for the prevention of dental caries.