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EDITOR We suggest that many typical clinical questions can be answered by
using a limited range of extracting, evaluating databases, which can be
interrogated with simple two step or three step search formulations.
Typically these sources contain several thousand references, as opposed
to several millions on large databases such as Medline or EMBASE
with their unfavourable signal to noise ratio.
The three sources that in our experience have a high yield of material
related to evidence based health care are the clinical queries option
in PubMed2; the Cochrane Library with its four sections
(systematic reviews, the CRD (Centre for Reviews and Dissemination)
database of reviews of effectiveness, the register of controlled
trials, and the NHS economic evaluation database)3; and
the TRIP (turning research into practice) database from the Centre for
Research Support, Cardiff.4
These three databases typically retrieve fewer than 10 references
provided that two or at most three relevant and discriminating terms
are selected for a simple search. We often suggest to trainees that
they should formulate their searches as if they were sending a
telegram: which two or three words would you transmit to a colleague to
ensure that he or she can imagine the clinical question? Thus the
question "How efficient is a single dose of a steroid for outpatient
croup?" suggests the search "croup and outpatient," which
identifies small sets (<10) containing a target
reference5 on any of the three databases mentioned above.
This pragmatic approach, although no substitute for systematic reviews
for those undertaking more extensive searches, is influenced by William
of Occam's principle of "if in doubt keep it simple" and is a
valid option for busy clinicians.
We agree with Guyatt et al that providing evidence based answers
to clinical questions requires intensive study and application if the
process is seen in the context of a systematic review of the original
literature.1 The main stumbling block remains the
difficulty of constructing complex searches appropriate for a range of
potential sources.
Reinhard Wentz
r.wentz{at}ich.ucl.ac.uk Institute of Child Health, London
WC1N 1EH
| 1. |
Guyatt GH, Meade MO, Jaeschke RZ, Cook DJ, Haynes RB.
Practitioners of evidence based care.
BMJ
2000;
320:
954-955 |
| 2. | Pubmed. www.ncbi.nlm.nih.gov:80/entrez/query/static/clinical.html |
| 3. | www.update-software.com/clibhome/clib.htm [password required]. |
| 4. | www.ceres.uwcm.ac.uk/frameset.cfm?section=Trip. |
| 5. |
Geelhoed GC, Turner J, Macdonald WBG.
Efficacy of a small single dose of oral dexamethasone for outpatient croup: a double blind placebo controlled clinical trial.
BMJ
1996;
313:
140-142 |
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