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another unmet need
It is effective but prejudice is preventing its use
Obesity, defined as having a body mass index
>30 kg/m2, is dramatically increasing in incidence in the
Western world. For example, 20 years ago 5% of the population in the
United Kingdom was obese; now 17% is.1 The annual
healthcare costs arising directly from obesity are at least £2bn
($3bn) in the United Kingdom and £45bn ($68bn) in the United
States.
2 3
Data from several sources have identified the
increased morbidity and mortality associated with
obesity.4 Most patients who are obese are treated with a
combination of advice on diet and lifestyle and in some cases with
drugs. However, for patients who have morbid obesity (body mass index
>40), this conservative approach is doomed to failure.
If left untreated patients who are morbidly obese (1-2% of the
population in the United Kingdom) have only a 1 in 7 chance of reaching
their normal life expectancy. A Cochrane review in 1997 noted that good
results had been obtained from surgery for obesity in these
patients.5 Over the past decade both the National Institutes of Health in the United States and the Scottish
Intercollegiate Guidelines Network have suggested that surgery is the
most effective treatment for selected patients who are morbidly obese;
both organisations have recommended that surgery be carried out more
frequently.
6 7
The selection criteria for surgery have
been established by the International Federation for the Surgery of
Obesity. The criteria are having a body mass index >40 or body mass
index of 35-40 in patients with serious comorbid disease that is
treatable by weight loss, being obese for a minimum of 5 years, having
had conservative treatment that failed, having no history of alcohol
misuse or major psychiatric illness, and being aged between 18 and 55 with acceptable operative risk as determined by preoperative
assessment. Women must avoid becoming pregnant within two years of the
operation. The surgery must be delivered in a multidisciplinary
environment. There should be a dietician or specialist nurse to counsel
the patient before and after surgery, a physician to assess fitness for
surgery and to exclude patients who have endocrine causes of obesity, a
psychologist to help the patient adjust to new eating habits after
surgery, an anaesthetist who is experienced in anaesthetising obese
patients, and a radiologist who can interpret special radiological investigations and carry out band adjustments if a gastric band has
been inserted.
Preliminary data from the Swedish obese subjects study, a
prospective matched cohort study of 2000 obese patients treated with
drugs who are being compared with 2000 obese patients who have been
treated with surgery, show that surgery is overwhelmingly better than
conservative management in improving quality of life, curing type 2 diabetes, controlling high blood pressure, reducing atheroma, improving
rates of employment, and in reducing costs to the health
service.8 In addition, data from other sources confirm the
efficacy of surgery for obesity in improving adverse lipid profiles,
sleep apnoea, joint problems, gastro-oesophageal reflux, urinary
incontinence, and asthma.9
If these data are so convincing why are fewer than 200 operations
carried out each year in the United Kingdom and why are many of them
funded privately? Firstly, there are few surgeons who are trained to
treat obesity. Secondly, society is ignorant and prejudiced against
patients with morbid obesity because there is a failure to understand
that obesity needs treatment just like any other disease. There is also
prejudice against surgeons who carry out this type of demanding
surgery. Some doctors consider surgery for obesity to be a waste of
resources, and others remember the poor results from earlier procedures
such as the jejunoileal bypass. There is also a lack of robust data on
the costs and benefits.
Since the advent of obesity surgery in the 1950s some procedures have
been discarded and others validated for their good long term results.
Data from over 14 000 patients on the international register of
obesity surgery shows that at 12 months vertical banded gastroplasty
and gastric bypass result in a mean loss of 53% and 72% of excess
weight, respectively, with operative mortality of 0.17%.10 Moreover, 93% of patients have no morbidity.
New technology has increased the range of procedures available; the
latest technique is the laparoscopic insertion of a gastric band, which
results in patients losing about 50-60% of their excess weight and
maintaining that loss for at least six years.11 Regardless of which procedure is carried out by a competent surgeon, it usually results in patients losing more than 50% of their excess body weight
during the first 1-2 years after surgery. If the patient is well
motivated and given lifelong counselling the weight loss is usually
permanent. However, attention should focus on the improvement of
comorbid conditions rather than on actual weight loss, since there are
good data to suggest that comorbidity decreases as a result of even
modest weight loss.12
A medical cure for this disease is unlikely to emerge for some time
because of the complexity of the disorder. Several surgical procedures
that have been well validated are available if patients can find
suitably trained surgeons with the necessary resources. Purchasers and
providers are prejudiced against surgery for obesity and it is accorded
a low priority, consequently it is being driven into the private sector
where only the rich can benefit. Insurance companies will not pay for
surgery because they do not understand that the procedures are cost
effective. In 1991 a survey of all general surgeons in the United
Kingdom showed there were only 38 obesity surgeons; most were doing
only a small number of operations.13 A repeat survey two
years ago showed that the number had dropped to 23.14 It
is little wonder that in this area the United Kingdom is so far behind
Europe, the United States, and Australasia.
An obesity surgeon should be available in all large hospitals together
with the relevant multidisciplinary team. Doctors and the public will
have to agitate for more resources to treat morbid obesity. When the
Swedish obese subjects study finally reports the details of the
advantages of surgery our profession will be under pressure to train
more obesity surgeons to alleviate this often fatal disease.
Postgraduate Medical School, University of Wales, Swansea SA2
8PP
Footnotes
Competing interests: JB is secretary of the British Obesity Surgery Society.
| 1. | Prescott-Clark P, Primatesta P, eds. Health survey for England 1996. London: HMSO, 1998. |
| 2. |
Bower H.
Guidelines tackle tidal wave of obesity.
BMJ
1996;
313:
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| 3. | Wolf AM, Colditz GA. The cost of obesity: the US perspective. Pharmacoeconomics 1994; 5(suppl 1): 34-37[Medline]. |
| 4. | Hubert HB. The importance of obesity in the development of coronary risk factors and disease: the epidemiological evidence. Ann Rev Public Health 1986; 7: 493-502[CrossRef][Medline]. |
| 5. | Glenny AM, O'Meara S, Melville A, Sheldon TA, Wilson C. The treatment and prevention of obesity: a systematic review of the literature. Int J Obes 1997; 21: 715-737[CrossRef][Medline]. |
| 6. |
National Institutes of Health.
Consensus Statement gastrointestinal surgery for severe obesity.
Nutrition
1996;
12:
397-402[CrossRef][Medline].
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| 7. | Scottish Intercollegiate Guidelines Network. Obesity in Scotland. Integrating prevention with weight management. Scottish Intercollegiate Guidelines Network, 1996. |
| 8. | Naslund I, Agren G. Is obesity surgery worthwhile [abstract]? Obes Surg 1999; 9: 326[CrossRef]. |
| 9. | Kral JG. The role of surgery in obesity management. Int J Risk Safety Med 1995; 7: 111-120. |
| 10. | Mason EE, Tang S, Renquist KE, Barnes DT, Cullen JJ, Doherty C, et al. A decade of change in obesity surgery. Obes Surg 1997; 7: 189-197[CrossRef][Medline]. |
| 11. | Belachew M, Legrand M, Vincent V, Lismonde M, Le Docte N, Deschamps V. Laparoscopic adjustable gastric banding. World J Surg 1998; 22: 955-963[CrossRef][Medline]. |
| 12. |
Jung RT.
Obesity as a disease.
Br Med Bull
1997;
53:
307-321 |
| 13. | Owen ERTC, Cooper MK, Kark AE. Obesity surgery in the UK: survey of 970 general surgeons. Br J Surg 1991; 73: 36-38. |
| 14. | Wright PD. The current status of bariatric surgery in the UK. Obes Surg 1998; 8: 364-365. |
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