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Deborah Josefson Inhaling helium to produce an amusing squeaky voice (a favourite
game for children in the United States and Europe) may not be the
innocuous party trick it seems, according to emergency medicine
physicians at the Wesley Center for Hyperbaric Medicine in Brisbane,
Australia (Annals of Emergency Medicine 2000;35:300-3).
Simon Mitchell and colleagues report the case of a previously healthy
27 year old man who inhaled helium and subsequently developed a stroke
with transient blindness and radio-graphic evidence of cortical
infarction. However, the man had inhaled the gas direct from a
pressurised canister, whereas most children who perform the trick The patient developed rigidity and lost consciousness within moments of
inhaling the helium. On arrival at the emergency room 15 minutes later,
he regained consciousness but was found to have complete visual loss
and evidence of cortical infarction.
The patient was diagnosed with a cerebral arterial gas embolism
occurring after inhaling helium; he was treated with hyperbaric oxygen.
His blindness resolved, and there was radiographic evidence of
regression of his stroke after four cycles of treatment with hyperbaric oxygen.
The patient in this report had inhaled helium direct from a high
pressure cylinder, causing blood vessels in his lungs to rupture and
allowing the gas to gain access to the pulmonary vasculature and
subsequently his brain. Before inhaling helium the patient had consumed
alcohol, smoked marijuana, and taken an amphetamine. These factors may
have lowered his threshold for the stroke but did not cause it.
This is the second reported case of stroke occurring after helium
inhalation. The first occurred in a 13 year old boy and showed that
even a single breath of helium can lead, albeit rarely, to stroke.
to
imitate the voice of Mickey Mouse
inhale the gas from helium filled balloons.

(Credit: AFP/MAYAVIDON )
Helium: safe in balloons but not in lungs?