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To study the determinants of adult disease Lamont et al
investigated the intima-media thickness of the carotid artery at age 49-51 years of several hundred men and women recruited at birth into
the Newcastle thousand families study and followed up through infancy
and childhood (p 273). In comparison with many previous studies, birth
weight and socioeconomic position at birth accounted for smaller
proportions of variance in cardiovascular disease risk in middle
age than did adult socioeconomic position, lifestyle, and
associated biological risk markers. A possible explanation may be
that this cohort experienced childhood after the war rather than before it.