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Martin Melville a Department of Cardiovascular Medicine,
University Hospital, Nottingham NG7 2UH, b British Heart Foundation Cardiovascular Statistics Unit,
Department of Mathematics, University of Nottingham, Nottingham
NG7 2RH
Correspondence to: M Melville
martin.melville{at}nottingham.ac.uk
Acute myocardial infarction affects around 250 000 people
each year in the United Kingdom. To our knowledge, medium term outcome and use of resources, other than revascularisation rates,1 have not been reported in a non-selected population.
All patients resident in Nottingham Health District who had
been admitted in 1992 for acute myocardial infarction to either of
Nottingham's two hospitals were identified from the Nottingham heart
attack register.2 We reviewed all hospital and general practitioner case notes for investigations, interventions,
readmissions, clinic visits, and symptoms up to August 1996. Data
on deaths were obtained from the Office for National Statistics.
Overall, 900 patients were admitted for myocardial infarction
(mean age 66.6 years; 561 men). Data extraction was completed in 899 (99.9%). The table shows the outcomes in the 695 patients who were
discharged alive.
In all, 537 patients received a clinic appointment on discharge (eight
did not attend and seven others had died). The remaining 158 did not
receive follow up Only 126 (24%) patients who were followed up had had a previous
myocardial infarction compared with 66 (42%) of those who were not
( Of the 488 patients alive at August 1998, 282 were recorded as having
or not having angina. Ninety eight had documented ongoing anginal
symptoms, of whom 45 required two or more antianginal drugs; none of
the 21 patients under the care solely of their general practitioner but
20 of the 24 patients under specialist review were being investigated.
Survivors of myocardial infarction comprise a mixed group with
varying degrees of underlying coronary disease, cardiac impairment, and
socioeconomic status, all of which influence health care
needs.3 The prospects for a patient surviving an
infarction are not particularly favourable, and patients require
hospital based care over years.
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Subjects, methods, and results
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Subjects, methods, and results
Comment
References
medical records did not indicate why.
2=20.47, P<0.001). The two groups did not differ in
size of infarct (as measured by rise in creatine kinase concentrations
(
2=1.51, P=0.219), location of infarct
(
2=0.72, P=0.399), or Killip score at hospital
presentation (
2=2.27, P=0.132)). Patients without follow
up were, however, less likely to have received thrombolysis
(
2=25.01, P<0.001) and to have been under the care of a
cardiologist; 142 of the 519 (27%) patients managed by a physician and
16 of the 176 (9%) managed by a cardiologist were not followed up
(
2=24.97; P<0.001). These patients were no more likely
to require readmission in the four years after infarction, but after
adjustment for age, sex, and previous infarction 79 (50%) had died
compared with 130 (24%) (z=3.44, P=0.001). There were no differences
in the proportion of deaths from coronary heart disease in the two groups (52 of the 78 deaths (67%) in those not followed up
v 88 of the 129 deaths (68%) in those followed up;
2=0.54, P=0.817). By the end of the study 135 patients
had never had an outpatient cardiology review and 62 had had no further hospital contact.
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Comment
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Subjects, methods, and results
Comment
References
Guidelines recommend formal follow up after discharge,4 but we found that clinical review was not universal. Opportunities were missed to optimise secondary prophylaxis and expedite cardiac rehabilitation, not least among those who did not receive routine follow up whose mortality was inexplicably high.
Demand did not fall with time: many survivors continued to attend clinic years after their infarction, reflecting the long term nature of coronary disease. Two thirds were readmitted with symptoms suggestive of further infarction (most on more than one occasion) or heart failure. Half underwent some form of cardiac investigation. Our angiography rate of 840 per 1 million population (63% of whom have had myocardial infarction) is close to British Cardiac Society recommendations5 but low by standards in the United States.
Opportunities to reduce the impact of disease are being missed. The
least that should be offered is to review all patients, optimise
treatment to minimise symptoms and cardiac risk, and advise general
practitioners when to refer for a specialist opinion.
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Acknowledgments |
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We thank the general practitioners of Nottingham for their cooperation.
Contributors: MM was responsible for study design, collecting follow up data, data analysis, and writing the paper. NB had the original idea for the study, was responsible for study design and collecting follow up data, and contributed to writing the paper. DG had the original idea for the study, was responsible for collecting the initial data on the register and for data analysis, contributed to writing the paper, and is guarantor for the study. JH originated the heart attack register and contributed to writing the paper. TY analysed the data and contributed to writing the paper. Jean Barton and Caroline Gray collected initial data for the heart attack register.
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Footnotes |
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Funding: The Nottingham heart attack register has been supported by the Department of Health since its inception in 1973.
Competing interests: None declared.
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References |
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| 1. |
Mark DB, Naylor CD, Hlatky MA, Califf RM, Topol EJ, Granger CB, et al.
Use of medical resources and quality of life after acute myocardial infarction in Canada and the United States.
N Engl J Med
1994;
331:
1130-1135 |
| 2. | Gray D, Keating NA, Murdock J, Skene AM, Hampton JR. Impact of hospital thrombolysis policy on out-of-hospital response to suspected myocardial infarction. Lancet 1993; 341: 654-657[Medline]. |
| 3. | Greenwood D, Packham C, Muir K, Madeley R. How do economic status and social support influence survival after initial recovery from acute myocardial infarction? Soc Sci Med 1995; 40: 639-647. |
| 4. | De Bono DP, Hopkins A. The management of acute myocardial infarction: guidelines and audit standards. Report of a workshop of the Joint Audit Committee of the British Cardiac Society and the Royal College of Physicians. J R Coll Physicians Lond 1994; 28: 312-317[Medline]. |
| 5. | British Cardiac Society. Strategic planning for cardiac services and the internal market: role of catheterisation in district general hospitals. Statement by the council of the British Cardiac Society 1998. Available at www.cardiac.org.uk/ (accessed 6 June 1999) |
(Accepted 10 February 1999)