Antiretroviral therapy does not prevent HIV related non-Hodgkin's lymphoma
Potent antiretroviral combination therapy has not significantly reduced
the incidence of non-Hodgkin's lymphoma in Swiss AIDS patients.
Ledergerber et al (p 23) analysed an ongoing prospective study that
includes most patients with HIV in Switzerland and found a reduction of
about 80% in the risk of most diseases, including Kaposi's sarcoma.
However, the reduction for non-Hodgkin's lymphoma was much smaller and
not significant. The authors suggest the factors promoting the
development of non-Hodgkin's lymphoma are not related to immune function.
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- Risk of HIV related Kaposi's sarcoma and non-Hodgkin's lymphoma with potent antiretroviral therapy: prospective cohort study
- Bruno Ledergerber, Amalio Telenti, and Matthias Egger
BMJ 1999 319: 23-24.[Extract] [Full Text] [PDF]
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