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Despite results showing that low cost antiretroviral
treatments were effective in reducing vertical transmission of HIV in Thailand and Africa, many developing countries are reluctant to introduce such programmes because of the high costs of the drugs. Söderlund et al (p 1650) used a computer simulation to assess the
cost effectiveness of antenatal HIV screening combined with various
interventions to prevent infection of children born to mothers with HIV
in South Africa. Low cost antiretroviral interventions seem to offer
good value for money in most settings with moderate and high prevalence
of HIV infection. Recommendations to avoid breast feeding, however,
seem appropriate only where there are reasonably high rates of infant survival.