No link supported between myocardial infarction and oral contraceptive use

There has been recent controversy over the association between thrombosis and different types of oral contraceptive. One study has suggested that modern oral contraceptives may be associated with a lower risk of myocardial infarction than older formulations. On p 1579 Dunn et al report the results of a large community based, case-control study in England, Scotland, and Wales that examined the association in women aged under 45. Oral contraceptive use was not associated with a significant increase in myocardial infarction. In particular, the type of progestogen seemed unimportant.


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Relevant Article

Oral contraceptives and myocardial infarction: results of the MICA case-control study Commentary: Oral contraceptives and myocardial infarction: reassuring new findings
Nicholas Dunn, Margaret Thorogood, Brian Faragher, Linda de Caestecker, Thomas M MacDonald, Charles McCollum, Simon Thomas, Ronald Mann, and Øjvind Lidegaard
BMJ 1999 318: 1579-1584. [Abstract] [Full Text] [PDF]




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