Evidence for antenatal toxoplasmosis screening is poor

Systematic review has shown that French and Austrian screening programmes for toxoplasma infection during pregnancy are based on poor evidence. Such screening is expensive, and some have questioned whether the interventions used to treat assumed infections do more good than harm. Wallon et al (p 1511) reviewed all evidence from comparative studies. Most studies had no controls or controls that were not directly comparable with the treatment group. The study found no good evidence of benefit from antenatal treatment. The authors recommend a careful trial before other countries introduce screening.


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Relevant Article

Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy
Martine Wallon, Christiane Liou, Paul Garner, and François Peyron
BMJ 1999 318: 1511-1514. [Abstract] [Full Text] [PDF]

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