Haemophilus influenzae type b vaccine is not linked to diabetes

Environmental risk factors for type 1 diabetes remain unknown. It has been speculated that some vaccines might trigger it, although data are lacking. On p 1169 Karvonen et al describe their findings from a nationwide randomised study on the association between Haemophilus influenzae type b vaccination and type 1 diabetes in Finland, which has the highest incidence of type 1 diabetes. The risk of type 1 diabetes during the first 10 years of life was similar in children vaccinated with H influenzae type b at 3 months and those immunised at 24 months only. Moreover, the incidence of the disease in the immunised children was no different from that in those children born during the two years before the start of the vaccination programme. It is unlikely that H influenzae vaccination causes type 1 diabetes in children.


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Relevant Article

Association between type 1 diabetes and Haemophilus influenzae type b vaccination: birth cohort study
Marjatta Karvonen, Zygimantas Cepaitis, and Jaakko Tuomilehto
BMJ 1999 318: 1169-1172. [Abstract] [Full Text] [PDF]




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