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In the management of patients with suspected appendicitis surgeons have
been taught to operate early enough to prevent perforation at the cost
of diagnostic accuracy. This has been especially important in women
because of the fear of peritoneal adhesions after perforated appendix
and subsequent tubular dysfunction and infertility. This attitude has
led to an error rate of up to 50% in women of reproductive age. There
is, however, no evidence that perforations can be prevented by such a
policy, and perforated appendix has not been established as a cause of
infertility in women. On p 963 Andersson et al report on a study of
fertility patterns in 9840 Swedish women aged under 15 when they
underwent appendicectomy and 47 590 age matched controls from the
general population. They found no adverse effects on fertility in women
with a history of perforated appendix. Explorations for suspected
appendicitis in women in whom the appendix is not inflamed cannot
therefore be justified on the grounds of prevention of infertility.