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Morbidity before diagnosis of primary hyperparathyroidism has not
been examined in population based studies. On p 848 Lundgren et al
report that screening for primary hyperparathyroidism in 5202 postmenopausal women found the disease in 109 (2.1%), 48 of whom were
working 5 years before the diagnosis. All women were unaware of the
disease and lacked traditional symptoms and complications of the
disorder. Case-control analysis of sick leave during the 5 years before
the diagnosis showed that women with hyperparathyroidism were 12 times
more likely to take sick leave for at least half the investigated
period. Doctors' certificates gave cardiovascular disease as the main
cause of such sick leave.