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A study last year suggested a very high relative risk of testicular
cancer in testes that had been biopsied at the time the men had
undergone orchiopexy for cryptorchidism. On p 729 Møller et al
describe their assessment of the risk of testicular cancer in an
unselected cohort of 830 men who had biopsies at the time of surgery
for 1026 undescended testes in 1971-92. The men were followed up
through the Danish cancer registry. Seven cases of testicular cancer
occurred in these 830 men between birth and 1994, but only three cases
occurred in men who had a testicular biopsy at the time of orchiopexy - a relative risk of 2.0. The authors conclude that their data do not
support the suggestion of a greatly increased risk of testicular cancer
in biopsied testes.
What can you learn from this BMJ paper? Read Leanne Tite's Paper+