High iron stores may predict development of type 2 diabetes
Most patients with haemochromatosis develop type 2 diabetes,
related to the amount of excess iron. Salonen et al tested the hypothesis that accumulation of iron predicts the development of type 2 diabetes by following 1038 randomly selected men from eastern Finland
aged 42-60 for four years (p 727): 41 men who developed diabetes were
compared with 82 closely matched controls. Men with high iron stores
were 2.4 times more likely to develop diabetes than those with lower
stores.
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- Relation between iron stores and non-insulin dependent diabetes in men: case-control study
- Jukka T Salonen, Tomi-Pekka Tuomainen, Kristiina Nyyssönen, Hanna-Maaria Lakka, and Kari Punnonen
BMJ 1998 317: 727-730.[Full Text] [PDF]
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