Preventive treatment for tuberculosis in adults infected with HIV does confer benefits
Preventive treatment for tuberculosis has long been known to reduce the
risk of active disease in those with latent tuberculosis infection or
recent close contact with an active case. What is the benefit of
preventive treatment to adults infected with HIV? On p 625 Wilkinson
et al report the results of a systematic review of randomised placebo
controlled trials from Uganda, Haiti, Kenya, and the United States.
Preventive treatment is of benefit to adults infected with HIV who have
latent tuberculosis (shown by a positive tuberculin skin test) by
reducing the number of cases of active disease and the number of
deaths.
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- Effect of preventive treatment for tuberculosis in adults infected with HIV: systematic review of randomised placebo controlled trials
- David Wilkinson, S B Squire, and Paul Garner
BMJ 1998 317: 625-629.[Abstract] [Full Text] [PDF]
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