White coat hypertension is associated with risk of left ventricular hypertrophy

Muscholl et al (p 565) studied left ventricular structure and function in a large population based cohort. They found a significant increase in left ventricular wall thickness and mass in subjects with white coat hypertension. The risk of left ventricular hypertrophy was greater in subjects with white coat hypertension than those with normtension. Systolic function assessed by M mode echocardiography showed values above normal in subjects with white coat hypertension whereas diastolic filling was no different from normotensive subjects after adjustment for confounders. Thus, they argue, the risk from white coat hypertension should not be disregarded.


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Relevant Article

Changes in left ventricular structure and function in patients with white coat hypertension: cross sectional survey
Michael W Muscholl, Hans-W Hense, Ulrich Bröckel, Angela Döring, Günter A J Riegger, and Heribert Schunkert
BMJ 1998 317: 565-570. [Abstract] [Full Text] [PDF]




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