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Although it is recognised that hospital patients are frequently
undernourished, it is not clear if routine protein energy supplementation improves patient outcomes. On p 495 Potter et al report
on a systematic review of the randomised controlled trials of routine
protein energy supplementation by the oral or enteral route. Patients
receiving supplements were more likely to show improvements in weight
and anthropometry and were less likely to die. However, when the
analysis was restricted to those trials clearly describing a good
methodological design, the observed benefits were diminished. Although
there may be significant and important health benefits from routine
prescribing of protein energy supplementation, further large pragmatic
trials are justified.