Giving albumin increases mortality in critically ill patients
The licensed indications for use of human albumin are the emergency
treatment of shock, acute management of burns, and clinical situations
associated with hypoproteinaemia. However, a systematic review of
randomised controlled trials by the Cochrane Injuries Group Albumin
Reviewers (p 235) showed that albumin administration results in six
extra deaths for every 100 patients treated. The authors call for an
urgent review of the use of human albumin solution in critically ill
patients.
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- Human albumin administration in critically ill patients: systematic review of randomised controlled trials • Why albumin may not work
- Cochrane Injuries Group Albumin Reviewers and Cochrane Injuries Group Albumin Reviewers
BMJ 1998 317: 235-240.[Abstract] [Full Text] [PDF]
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