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Although it is recommended that patients with cystic fibrosis are cared
for by specialist centres there is no direct evidence to support the
provision of these services. On p 1771 Mahadeva et al compare patients
with cystic fibrosis who never had specialist care with those attending
the adult cystic fibrosis centre in Manchester. The results show that
specialist management in a paediatric and adult cystic fibrosis centre
results in a greatly improved body mass index and lung function despite
earlier colonisation with Pseudomonas aeruginosa. These
data support the development of cystic fibrosis centres and suggest
that patients with cystic fibrosis should receive centre care at the
earliest possible age if they are to gain the impetus for prolonged
survival in adulthood.