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Studies of smoking and cardiovascular disease may have
underestimated the risk in women because until recently women's
smoking habits have differed greatly from men's. During the past few
decades, however, women have taken up smoking like men. Using data from three large prospective studies in Copenhagen that included many women
who were heavy smokers, Prescott et al (p 1043) found that the smoking
related risk of myocardial infarction was 50% higher in women than in
men. This difference may be caused by interactions between
components of tobacco smoke and hormonal factors.