Epidemiological data are of little use in guiding clinical practice

Epidemiological studies investigate overall effects within populations, but clinicians need information about specific risks and benefits for individual patients. Hannaford and Owen-Smith (p 984) reviewed all published studies of the risk of cardiovascular disease in current users of combined oral contraceptives in order to assess the usefulness of the data in defining the risk for young, healthy women who do not smoke. Of the 74 papers identified, only five provided information that directly addressed the clinical question, although 14 others probably had the potential to answer the question after reanalysis.


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Relevant Article

Using epidemiological data to guide clinical practice: review of studies on cardiovascular disease and use of combined oral contraceptives
Philip C Hannaford and Vicci Owen-Smith
BMJ 1998 316: 984-987. [Abstract] [Full Text] [PDF]




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