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Patients with type 2 diabetes mellitus have an increased incidence of
disease related to atheroma and decreased life expectancy. On p 823
the UK Prospective Diabetes Study Group reports on mortality and
coronary artery disease in over 3000 patients with recently diagnosed
type 2 diabetes and no evidence of disease related to atheroma at
diagnosis. The study showed an increased standardised mortality ratio
after 5 years from diagnosis. Over a median of 8 years, 11% of
patients had a myocardial infarction or developed angina. The risk
factors for coronary artery disease were raised values of low density
lipoprotein cholesterol and decreased values of high density
lipoprotein cholesterol, hyperglycaemia, hypertension, and smoking.