Published 23 September 2009, doi:10.1136/bmj.b3835
Cite this as: BMJ 2009;339:b3835

Endgames

Statistical question

Positive predictive value

Siva K Talluri, clinical assistant professor

1 Mclaren Regional Medical Center, Flint, MI 48532, USA

talluri1@msu.edu

The first 150 words of the full text of this article appear below.

A 50 year old man presents with a sore throat. You suspect streptococcal pharyngitis and request a rapid streptococcal antigen test. The sensitivity of this test is 80% and the specificity is 95%. The prevalence of streptococcal pharyngitis in adults with pharyngitis is 10%.

What is the likelihood that the patient has streptococcal pharyngitis if the rapid streptococcal antigen test is positive?

a) 64%
b) 80%
c) 95%
d) 98%

a—The likelihood that the patient has streptococcal pharyngitis if the rapid streptococcal antigen test is positive is termed the positive predictive value of the test. In general, the positive predictive value of any test indicates the likelihood that someone with a positive test result actually has the disease.

Predictive values are useful to the clinician as they indicate the likelihood of disease in a patient when the test result is positive (positive predictive value) or the likelihood that the . . . [Full text of this article]


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Rapid Responses:

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Statistical theory is never easy to explain or present
Zekria Ibrahimi
bmj.com, 7 Oct 2009 [Full text]
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bmj.com, 8 Oct 2009 [Full text]



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