Published 14 September 2009, doi:10.1136/bmj.b3758
Cite this as: BMJ 2009;339:b3758

Letters

A/H1N1 flu pandemic

Roche responds

The first 150 words of the full text of this article appear below.

The use of oseltamivir (Tamiflu) in children and the development of resistance from widespread usage have been much debated.1

Antiviral treatments are currently the only available therapeutic option to prevent and treat infection with the A/H1N1 flu virus. The product summary for oseltamivir shows that it is effective and well tolerated in children.

The European Medicines Agency approves oseltamivir to treat and prevent flu in those aged 1 year and over on the basis of a positive benefit and risk assessment. The product summary shows that in otherwise healthy children (under 12s) who had fever with either cough or coryza, treatment started within 48 hours of the onset of symptoms significantly reduces the time to alleviation of illness by 1.5 days compared with placebo. The incidence of acute otitis media was reduced from 26.5% in the placebo group to 16% in the oseltamivir group. In a group of asthmatic children, . . . [Full text of this article]

Michelle Rashford, medical director1

1 Roche Products, Welwyn Garden City, Hertfordshire AL7 1TW

michelle.rashford@roche.com


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