Should HPV vaccine be given to men?

doi:10.1136/bmj.b4127

Published 8 October 2009, doi:10.1136/bmj.b4127
Cite this as: BMJ 2009;339:b4127

Editorials

Should HPV vaccine be given to men?

The best investment is to vaccinate preadolescent females, notmales

The first 150 words of the full text of this article appear below.

On 9 September 2009, a US Food and Drug Administration (FDA)advisory panel recommended that the FDA approve Gardasil (Merck)—thequadrivalent human papillomavirus (HPV) vaccine against HPVtypes 6, 11, 16, and 18—for use in males aged 9-26 yearsto prevent genital warts (condyloma acuminata). The vaccinewas 90% effective in preventing genital warts and reducing theincidence of persistent HPV 6 and HPV 11 anogenital infections¹—whichcause about 90% of genital warts in HPV niaive males—and79% effective at reducing of the incidence of persistent anogenitalHPV 16 infections and 96% of HPV 18 infections. Therefore, carriagein the male population of the two HPV genotypes that cause 70%of cervical cancer worldwide in women could be greatly reducedby widespread HPV vaccination. The question is should men bevaccinated?

In the linked study (doi:10.1136/bmj.b3884), Kim and Goldiereport an independent analysis of the cost effectiveness . . . [Full text of this article]

Philip E Castle, investigator¹, Isabel Scarinci, associate professor²

¹ Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-7234, USA, ² Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL 35205, USA

castlep@mail.nih.gov

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

StumbleUpon Add to Technorati

Technorati What's this?

Relevant Articles

What about male specific HPV related diseases?: Carlo Foresta, Alberto Ferlin, and Andrea Garolla
BMJ 2009 339: b4514. [Extract] [Full Text]

Cost effectiveness analysis of including boys in a human papillomavirus vaccination programme in the United States: Jane J Kim and Sue J Goldie
BMJ 2009 339: b3884. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

Foresta, C., Ferlin, A., Garolla, A. (2009). What about male specific HPV related diseases?. BMJ 339: b4514-b4514 [Full text]

Rapid Responses:

Read all Rapid Responses

HPV prevention- a broader view: David B G Hawker
bmj.com, 17 Oct 2009 [Full text]
A longer term view: Sarah C Walpole
bmj.com, 19 Oct 2009 [Full text]
HPV Vaccination in males- a holistic view: Margaret E Heffernan OAM
bmj.com, 22 Oct 2009 [Full text]
Should HPV Vaccine be given to Men?: CV PRAVEEN, et al.
bmj.com, 24 Oct 2009 [Full text]
Re: A longer term view: Philip Castle
bmj.com, 26 Oct 2009 [Full text]
Re: HPV prevention- a broader view: Philip Castle
bmj.com, 26 Oct 2009 [Full text]
Re: HPV Vaccination in males- a holistic view: Philip Castle
bmj.com, 26 Oct 2009 [Full text]