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Published 12 November 2009, doi:10.1136/bmj.b4118
Cite this as: BMJ 2009;339:b4118
Philip Wood, consultant immunologist1, Daniel Peckham, consultant respiratory physician2
1 Department of Clinical Immunology, St Jamess University Hospital, Leeds, LS9 7TF, 2 Department of Respiratory Medicine, St Jamess University Hospital
Correspondence to: P Wood philip.wood@leedsth.nhs.uk
Repeated respiratory tract infections in an apparently otherwise well young person should raise suspicions of underlying immunodeficiency or other respiratory disease
| The first 150 words of the full text of this article appear below. |
A 29 year old man presents to the surgery with a third episode of respiratory tract infection in three months, having had one admission to hospital with proved pneumococcal pneumonia five months ago. He is a previously well non-smoker who does not have asthma, any previous diagnosed chronic medical condition, or recent history of foreign travel.
He has no weight loss or night sweats. On examination he has bilateral basal crackles in the lungs, normal tympanic membranes, no facial tenderness, and no lymphadenopathy or splenomegaly. A full blood count is normal; random and fasting blood glucose, urea, creatinine, and liver enzymes are all normal, and urinalysis is negative for blood and protein. Sputum culture identifies the presence of Haemophilus influenzae. A chest radiograph is reported as normal.
In 2007 the reported prevalence for acute respiratory infections in the United Kingdom was 1599/10 000 population, with peaks in early childhood
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