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Published 18 August 2009, doi:10.1136/bmj.b3346
Cite this as: BMJ 2009;339:b3346
| The first 150 words of the full text of this article appear below. |
Hatton and colleagues say that nodules in hyperthyroid patients are unlikely to be malignant, suggesting that no further investigation is required if thyroid function tests indicate hyperthyroidism.1 However, the presence of a solitary or dominant thyroid nodule in a patient with biochemical evidence of hyperthyroidism is one of the few remaining indications for isotope scanning of the thyroid.
An autonomous "hot" nodule is indeed unlikely to be malignant, and fine needle aspiration is not indicated. However, if the patient has one nodule, others may (and often will) be present. If thyroid stimulating hormone is suppressed, you need to be sure that the palpable nodule is suppressing it: an impalpable hot nodule may exist elsewhere in the gland, and the presenting lesion may be cold and require fine needle aspiration.
To summarise, in euthyroid patients, isotope scanning to characterise nodules is not indicated because they will either be cold or warm,
Bob Bury, consultant radiologist1
1 Leeds Teaching Hospitals Trust, Leeds LS1 3EX
bobbury@gmail.com