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Published 6 August 2009, doi:10.1136/bmj.b2476
Cite this as: BMJ 2009;339:b2476
Steroids reduce pain in the first day, but data on harms are lacking
| The first 150 words of the full text of this article appear below. |
In the linked study (doi:10.1136/bmj.b2976), Hayward and colleagues report a useful and well performed systematic review in a highly topical area.1 Clinicians and patients need information about interventions other than antibiotics for sore throat for several reasons—the benefit of antibiotics for most patients is modest2 3; the use of antibiotics should be minimised because of the danger of resistance3 4; and other effective treatments, apart from the use of analgesics, anti-inflammatory drugs,5 and possibly Echinacea, are lacking.6 This systematic review provides evidence that in the first 24 hours steroids may help resolve pain (the likelihood of resolution was increased threefold, number needed to treat (NNT) 3.7) and reduce the mean time to onset of pain relief by six hours. Furthermore, given that most patients in the included studies had antibiotics, although the effect of antibiotics is modest, the effect of steroids in those not receiving antibiotics may
Paul Little, professor of primary care research
1 University of Southampton, Southampton SO16 5ST
P.Little@soton.ac.uk
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