Bleeding and resistance

doi:10.1136/bmj.b1927

Published 20 May 2009, doi:10.1136/bmj.b1927
Cite this as: BMJ 2009;338:b1927

Letters

Clopidogrel

Bleeding and resistance

The first 100% of the full text of this article appears below.

The review of clopidogrel in acute coronary syndromes does notmention the management of bleeding in patients taking clopidogrel.¹Unlike aspirin, whose antiplatelet effects can be predictablyovercome by platelet transfusion, clopidogrel has no reliableantidote. Another omission is clopidogrel resistance, the subjectof a recent review.²

Cite this as: BMJ 2009;338:b1927

Jonathan Ball, consultant in intensive care¹

¹ St George’s Hospital, London SW17 0QT

jball@sgul.ac.uk

Competing interests: None declared.

Chua D, Ignaszewski A. Clopidogrel in acute coronary syndromes. BMJ 2009;338:b1180. (14 April.)[Free Full Text]
Dominick J, Angiolillo MD. Variability in responsiveness to oral antiplatelet therapy. Am J Cardiol 2009;103(suppl 1):27-34A.