Published 23 March 2009, doi:10.1136/bmj.b1197
Cite this as: BMJ 2009;338:b1197

Letters

Resting heart rate as predictor

What about absolute risks?

The first 150 words of the full text of this article appear below.

It is a fundamental principle in public health that you should never quote a relative risk without also giving the absolute risk.1 Failure to follow this simple precept results in the weekly health scares that engage the popular press, when an increased relative risk is taken as a threat to the individual.

Hsia et al flagrantly ignore this principle when they claim that "resting heart rate independently predicts myocardial infarction or coronary death in women."2 They base this assertion on a hazard ratio of 1.26 (95% confidence interval 1.11 to 1.42) for these events in women above the top quintile for heart rate compared with women below the bottom. They do not quote absolute risks. Using some simplifying assumptions (equating hazard rate to relative risk, assuming total events in lower fifth and upper fifth is proportional to the number of subjects in these groups), I estimated the absolute risk of . . . [Full text of this article]

Michael J Campbell, professor of medical statistics1

1 Medical Statistics Group, ScHARR, University of Sheffield, Sheffield S1 4DA

m.j.campbell@sheffield.ac.uk


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Relevant Article

Resting heart rate as a low tech predictor of coronary events in women: prospective cohort study
Judith Hsia, Joseph C Larson, Judith K Ockene, Gloria E Sarto, Matthew A Allison, Susan L Hendrix, Jennifer G Robinson, Andrea Z LaCroix, JoAnn E Manson, and for the Women’s Health Initiative Research Group
BMJ 2009 338: b219. [Abstract] [Full Text] [PDF]




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