Published 4 March 2009, doi:10.1136/bmj.b611
Cite this as: BMJ 2009;338:b611

Practice

Rational Imaging

Incidental thyroid nodule

Chirag N Patel, specialist registrar in radiology 1, Georgina Gerrard, consultant clinical oncologist2, Andrew F Scarsbrook, consultant radiologist and nuclear medicine physician1

1 Departments of Radiology and Nuclear Medicine, St James’s University Hospital, Leeds Teaching Hospital, Leeds LS9 7TF, 2 Department of Clinical Oncology, St James’s University Hospital, Leeds Teaching Hospital, Leeds LS9 7TF

Correspondence to: A F Scarsbrook andrew.scarsbrook@leedsth.nhs.uk

Thyroid nodules may be coincidentally detected as a result of neck imaging, and most are benign; the authors discuss how best to decide which nodules are most likely to be malignant and require further evaluation

The first 150 words of the full text of this article appear below.


  • Thyroid nodules are very common, and the overwhelming majority are benign
  • Thyroid nodules may be coincidentally detected as a result of the increasing use of neck imaging
  • No imaging modality can reliably differentiate between benign and malignant thyroid nodules, but ultrasonography is the best technique for evaluating nodules and triaging those that require histological evaluation
  • Ultrasound guided fine needle aspiration cytology is accurate, cheap, and safe in most cases, but local resources vary
  • Metabolically active thyroid nodules detected on fused positron emission tomography and computed tomography (PET-CT) are associated with a 1 in 3 chance of malignancy and should be further evaluated
  • PET-CT may have a future role in reducing unnecessary surgery in patients with indeterminate cytology because of its high negative predictive value


A 78 year old man presented with haemoptysis and was found to have a bronchial tumour at bronchoscopy. He was referred for a 18fluorine fluorodeoxyglucose PET-CT . . . [Full text of this article]


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