Kidney function and the risk of cardiovascular disease

doi:10.1136/bmj.b1307

Published 29 June 2009, doi:10.1136/bmj.b1307
Cite this as: BMJ 2009;338:b1307

Editorials

Kidney function and the risk of cardiovascular disease

More accurate measures of kidney function are needed to identifythose at risk

The first 150 words of the full text of this article appear below.

Several studies have shown that people with impaired kidneyfunction are at higher risk of cardiovascular disease and death,¹² although the reasons for this are unclear. In the linked study(doi:10.1136/bmj.b2392), Kurth and colleagues examine data fromfemale health professionals aged 45 and over enrolled in theWomen’s Health Study (WHS) to assess the association ofkidney function with cardiovascular disease and mortality.³

The WHS is a randomised trial of low dose aspirin and vitaminE supplements conducted in nearly 40 000 relatively healthy,predominantly white, female healthcare professionals in theUnited States. Serum creatinine was assayed in 27 939 participantsusing a rate blanked method based on the Jaffé reaction,and estimated glomerular filtration rate (GFR) was calculatedwith the four-variable Modification of Diet in Renal DiseaseStudy (MDRD) equation. Over a mean of 12 years, 1199 cardiovascularevents and 856 deaths occurred. When compared with an . . . [Full text of this article]

Daniel E Weiner, assistant professor , Dena E Rifkin, instructor

¹ Division of Nephrology, Tufts Medical Center, Boston, MA 02111, USA

dweiner@tuftsmedicalcenter.org

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

StumbleUpon Add to Technorati

Technorati What's this?

Relevant Article

Kidney function and risk of cardiovascular disease and mortality in women: a prospective cohort study: Tobias Kurth, Paul E de Jong, Nancy R Cook, Julie E Buring, and Paul M Ridker
BMJ 2009 338: b2392. [Abstract] [Full Text] [PDF]