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Published 22 April 2009, doi:10.1136/bmj.b1461
Cite this as: BMJ 2009;338:b1461
Richard Lee, ST2 academic clinical fellow, allergy and respiratory medicine, Rhodri Martin, ST1 core medical training , David DCruz, consultant rheumatologist
1 Lupus Research Unit, Rayne Institute, St Thomas Hospital, London SE1 7EH
Correspondence to: D DCruz david.d'cruz@kcl.ac.uk
| The first 150 words of the full text of this article appear below. |
A 60 year old man with Wegeners granulomatosis who was clinically stable on methotrexate presented with a two day history of haemoptysis. On examination he was febrile, with bibasal crepitations and bronchial breath sounds in the left upper zone.
Pulse oximetry showed an oxygen saturation of 96% on air. A full blood count showed that his haemoglobin was 134 g/l, white blood cells were 18.4x109/l (neutrophils 15.3x109/l), and serum creatinine was 74 µmol/l. He had a titre of 1:160 on recent serological testing for cytoplasmic staining antineutrophil cytoplasmic antibodies.
Urinalysis detected trace amounts of protein and blood, but he had no dysmorphic red cells or casts on urine microscopy.
He underwent computed tomography of the chest and chest radiography (figs 1
and 2
).
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