Published 19 November 2008, doi:10.1136/bmj.a2304
Cite this as: BMJ 2008;337:a2304

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A patient with β thalassaemia major and back pain

Dimitris A Tsitsikas, Specialist registrar in haematology, Filipa A Barroso, Specialist registrar in haematology, Paul Telfer, Senior lecturer in haematology, Banu Kaya, Consultant haematologist, Jane Evanson, Consultant neuroradiologist, Andrew Provan, Senior lecturer in haematology

1 Barts and the London NHS Trust

dimitristsitsikas@hotmail.com

The first 150 words of the full text of this article appear below.

A 37 year old man with β thalassaemia major presented to the haematology day unit with a three week history of increasing back pain. The pain was aggravated by movement and the patient found it increasingly difficult to walk. He said he felt "wobbly" on his feet. He had no history to indicate sphincter dysfunction. He was regularly transfused and his haemoglobin at presentation was 11.3 g/dl.

On neurological examination, his tone was normal, and he had normal power (5/5) in all muscle groups of his lower limbs. He had brisk knee jerks and, to a lesser extent, ankle jerks bilaterally, with an upgoing plantar response on the right side and an equivocal reaction on the left. He had hypoaesthesia of his legs and torso with a sensory level at T5. He showed no signs of cerebellar dysfunction. His gait was not assessed. The rest of the examination was unremarkable. . . . [Full text of this article]


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