BMJ 2008;336:833 (12 April), doi:10.1136/bmj.39371.652604.94
Practice
10-minute consultation
Suspected premature menopause
Georgina Louise Jones, non-clinical senior lecturer1,
William Ledger, head of academic unit of reproductive and developmental medicine2,
Caroline Mitchell, general practitioner and clinical senior lecturer3
1 Health Services Research Section, School of Health and Related Research, University of Sheffield, Sheffield S1 4DA,
2 University of Sheffield, Jessop Wing Hospital, Sheffield S10 2JT,
3 Division of Primary Medical Care, University of Sheffield, Northern General Hospital, Sheffield S5 7AU
Correspondence to: G L Jones g.l.jones@sheffield.ac.uk
| The first 150 words of the full text of this article appear below. |
A 34 year old woman who attends your surgery has a 12 month history of irregular periods (increasing cycle length). She has never been pregnant. Her mothers menopause began in her late 30s, and your patient is worried about her own current and future fertility.
What issues you should cover
- Discuss the possibility of premature ovarian failure, but tell her this is uncommon at age 34 and that other causes of menstrual irregularity—the most common of which would be polycystic ovary syndrome (PCOS) with anovulation—can usually be treated successfully. However, premature ovarian failure does have a familial component, so it is important to exclude this important possible diagnosis, as it has major implications for her future fertility.
- Ask about her menstrual history: age at menarche, dysmenorrhoea or menorrhagia, cycle length in the past.
- Ask about signsof PCOS (weight gain, hirsutism, acne, acanthosis nigricans) and family history of diabetes.
- Consider other causes of oligomenorrhoea and their . . . [Full text of this article]
Useful resourcesInternet resources for patientsWhat you should do

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Relevant Article
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Articles recommendation of HRT is highly questionable
- Mark D Lewars
BMJ 2008 336: 1033-1034.
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This article has been cited by other articles:
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Lewars, M. D
(2008). Article's recommendation of HRT is highly questionable. BMJ
336: 1033-1034
[Full text]
Rapid Responses:
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- 10 minute consultation:suspected premature menopause
- Mohammad A Javid
bmj.com, 11 Apr 2008
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- Re: Highly Questionable Recommendation of HRT.
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bmj.com, 13 May 2008
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