BMJ  2008;336:529 (8 March), doi:10.1136/bmj.39507.688611.DB

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Poor drug adherence after heart attack puts patients at greater risk of death at one year

Barbara Kermode-Scott

1 Toronto

The first 150 words of the full text of this article appear below.

Patients who do not order all the drugs prescribed after discharge from hospital after acute myocardial infarction have a greater risk of death at one year, a large population based cohort study in Ontario has shown (Circulation 2008;117:1028-36 doi: 10.1161/CIRCULATIONAHA.107.706820). And only three out of four patients ordered all of the drugs that they had been prescribed.

Researchers at the Institute for Clinical Evaluative Sciences in Toronto reported that primary non-compliance, when a patient receives a first prescription but does not order the drugs, was associated with a greater risk of death at one year after myocardial infarction even after adjusting for other known factors that may be associated with mortality.

Within 120 days of discharge, patients who had not ordered any of their drugs had an 80% greater chance of death at one year than patients who had ordered all their drugs (odds ratio 1.80, 95% confidence . . . [Full text of this article]


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