Management of depression in adults

doi:10.1136/bmj.39478.609097.BE

BMJ 2008;336:435-439 (23 February), doi:10.1136/bmj.39478.609097.BE

Clinical Review

Management of depression in adults

Markku Timonen, professor of general practice¹, Timo Liukkonen, senior consultant²

¹ Institute of Health Sciences, University of Oulu, Box 5000, FIN-90014, Finland, ² Department of Psychiatry, Savonlinna Central Hospital, Finland

Correspondence to: M Timonen markku.timonen@oulu.fi

The first 150 words of the full text of this article appear below.

A study by the World Health Organization ranked depression thefourth global burden of disease and found it to be the largestnon-fatal burden of disease, with nearly 12% of total yearslived with disability.¹ According to the cross sectional WHOworld health survey, carried out in all regions of the world(60 countries), the one year prevalence of a depressive episode(international classification of diseases, 10th revision) was3.2% (95% confidence interval 3.0% to 3.5%). In patients withseveral medical conditions the prevalence of depression exceedsthat of the general population,² with 5-10% of patients affectedin primary care and 10-14% of patients under general hospitalcare.³ The diagnosis and treatment of depression by generalpractitioners is not, however, always optimal.⁴ ⁵ We reviewthe presentation and assessment of depression and discuss theoptions for its effective treatment and management.

Somatisation is one of the most important singleproblems associated . . . [Full text of this article]

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