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BMJ 2008;336:215-216 (26 January), doi:10.1136/bmj.39381.597454.AE
Kimme L Hyrich, clinical lecturer and consultant in rheumatology1
1 ARC Epidemiology Unit, University of Manchester, Manchester M13 9PT
kimme.hyrich@manchester.ac.uk
| The first 150 words of the full text of this article appear below. |
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Rheumatoid arthritis affects 1% of adults and is associated with progressive joint damage and disability and increased mortality. Treatment with disease modifying anti-rheumatic drugs (DMARDs), such as methotrexate, has been shown to reduce the progression of radiologically evident joint damage and improve long term disability. A shift towards starting DMARD treatment as early as possible has therefore occurred. Guidelines recommend that patients should be referred early, ideally within six weeks of the onset of symptoms,1 and that DMARDs should be started within 12 weeks of onset.2
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