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BMJ 2007;335:1227 (15 December), doi:10.1136/bmj.39423.581042.DB
Geoff Watts
| The first 150 words of the full text of this article appear below. |
An initiative from the World Health Organization has been launched to make drugs as simply and safely available to children as they are to adults.
Speaking last week at the launch in London, WHOs assistant director general, Howard Zucker, said that "there is a gap between the availability of childrens medicines and the actual need. That gap is global and must be addressed."
The problem is not new. "Its a reality weve lived with for many years," Dr Zucker admitted. Most drugs are developed for and tested in adults. Less than a third come in a form appropriate for children.
As a result, many children are treated using drugs that are effectively unlicensed. Medical staff may be obliged to estimate the appropriate fraction of an adult dose, and then crush tablets or extract part of the contents of a capsule.
One study by WHO has shown that drug errors are
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