BMJ  2007;335:1113 (1 December), doi:10.1136/bmj.39409.458611.DB

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Diabetes expert accuses drug company of "intimidation"

Bob Burton

Canberra

The first 150 words of the full text of this article appear below.

The former chairman of research and development at GlaxoSmithKline, Tadataka Yamada, has been asked by a US Senate committee to explain his role in what it describes as the "intimidation" of John Buse, a professor of medicine at the University of North Carolina.

In 1999 Dr Buse raised questions about the cardiovascular safety of the diabetes drug rosiglitazone, which is marketed as Avandia (BMJ 2007;334:1237 doi: 10.1136/bmj.39244.394456.DB). He was speaking at a symposium organised by the American Diabetes Association.

A report by the Senate Finance Committee staff has shown that a company official emailed Dr Yamada proposing that a "firm letter" be written to Dr Buse containing a warning that "the punishment will be that we will complain up his academic line and to the CME [continuing medical education] granting bodies that accredit his activities."

In response Dr Yamada wrote: "I think there are two courses of action. . . . [Full text of this article]


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