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BMJ 2007;335:743 (13 October), doi:10.1136/bmj.39360.499097.DB
Susan Mayor
London
| The first 150 words of the full text of this article appear below. |
No good evidence exists that individually tailored prescriptions of a mixture of herbs are effective, concludes a systematic review published last week.
The study reviewed all available studies of individualised herbal medicine for any indication (Postgraduate Medical Journal 2007;83:633-7). The researchers, from the Universities of Exeter and Plymouth, found only three randomised controlled trials out of 1300 studies they identified that they considered were of sufficient quality to draw meaningful conclusions. These three trials showed no convincing evidence of benefit.
One trial, involving patients with osteoarthritis of the knee, showed a non-significant trend favouring active treatment over placebo. However, the researchers said that this trend probably resulted from large differences at baseline and regression to the mean.
In a trial of patients with irritable bowel syndrome, individualised herbal treatment was better than placebo in four of the five outcomes tested but was inferior to a standardised herbal treatment (a
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