BMJ  2007;335:446-448 (1 September), doi:10.1136/bmj.39302.509005.AE

Practice

Diagnosis and management of chronic fatigue syndrome or myalgic encephalomyelitis (or encephalopathy): summary of NICE guidance

R Baker, chair of the guideline group1, E J Shaw, deputy chief executive2

1 Department of Health Sciences, University of Leicester, Leicester LE1 6TP , 2 National Collaborating Centre for Primary Care, Royal College of General Practitioners, London E1 8EW

Correspondence to: E J Shaw cfs_me@rcgp.org.uk

The first 150 words of the full text of this article appear below.

Why read this summary?

Data from other countries indicate that chronic fatigue syndrome (also known as myalgic encephalomyelitis or myalgic encephalopathy) (CFS/ME) is relatively common (affecting at least 0.2-0.4% of the population), although good epidemiological data for the United Kingdom are lacking. Many different potential aetiologies for CFS/ME have been investigated, including neurological, endocrine, immunological, genetic, psychiatric, and infectious, but the aetiology cannot yet be fully explained. CFS/ME can cause prolonged illness and disability and substantially affect patients and their families. Although most patients have mild or moderate symptoms, some have severe CFS/ME and are housebound or even unable to move from their bed. Uncertainties about diagnosis and management may exacerbate the impact of symptoms, and patients often encounter delays in diagnosis and difficulty accessing information, support, and potentially helpful therapies.1 This article summarises the most recent guidance from the National Institute for Health and Clinical Excellence (NICE) on diagnosing and managing this condition.2

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