BMJ  2007;335:37-41 (7 July), doi:10.1136/bmj.39252.591806.47

Clinical Review

Managing smoking cessation

Paul Aveyard, National Institute of Health research career scientist1, Robert West, professor of health psychology and director of tobacco studies2

1 Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT , 2 Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT

Correspondence to: P Aveyard p.n.aveyard@bham.ac.uk

The first 150 words of the full text of this article appear below.

Cross sectional studies show that most smokers in countries such as the United Kingdom and the United States report that they want to stop and intend to stop at some point.1 The rate of attempts to stop is high—78 attempts per 100 smokers per year in the UK—with many smokers making several attempts in a year.2 Nearly half of all smokers expect not to be smoking in a year's time,3 but only 2-3% actually stop permanently each year.3

The most common reasons smokers give for smoking are stress relief and enjoyment,4 but the main reason is nicotine dependence. Nicotine acts in the midbrain, creating impulses to smoke in the face of stimuli associated with smoking.5 Consequent changes in brain chemistry also produce "nicotine hunger" when a smoker goes without nicotine. A third mechanism underlying nicotine dependence is nicotine withdrawal: unpleasant mood and physical symptoms that occur on abstinence and are . . . [Full text of this article]

Summary points


Why should healthcare professionals help patients stop smoking?


How should I broach the subject of smoking?


Nicotine replacement therapy

Antidepressants


A new drug


Choosing treatment


How do I treat special groups?


Light and social smokers
Pregnant women
Adolescents

Is behavioural support or counselling effective?


Other strategies


How do I help my patients avoid relapse?


Conclusions


Prescribing smoking cessation drugs
Bupropion
Nortriptyline
Varenicline
Nicotine replacement patches
A patient's story
Methods
Ongoing research and unanswered questions
Additional educational resources
Information resources for patients

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